Cabozantinib 20mg and 40mg tablets

Afinitor 5mg & 10mg Tablets Online

  • Innovator Brand Name: Cabometyx
  • API: Cabozantinib
  • Packaging: Tablets
  • Strength: 20 mg/40 mg/60 mg

Cabozantinib is a kinase inhibitor used for the treatment of 

  • patients with advanced renal cell carcinoma (RCC).
  • patients with hepatocellular carcinoma (HCC) who have previously received medicine sorafenib.  
  • patients with advanced renal cell carcinoma (RCC), as a first-line treatment along with medicine nivolumab.

The recommended dosage of cabozantinib tablets for RCC and HCC is 60 mg once daily without meals until the patient no longer experiences benefit or experiences unacceptable toxicity. 

The recommended dosage of Cabozantinib for advanced RCC along with nivolumab is 40 mg orally, once daily, administered with nivolumab 240 mg every 2 weeks or 480 mg every 4 weeks. 

Do not administer Cabozantinib with food. Administer at least 60 minutes before or at least 120 minutes after eating. Swallow Cabozantinib tablets whole. Do not crush the tablets. It is not advisable to replace or substitute Cabozantinib tablets with cabozantinib capsules. Stop treatment with Cabozantinib at least 28 days before scheduled surgery, including dental surgery. Do not take any missed dose of Cabozantinib within 12 hours of the very next scheduled dose.

The common side effects with Cabozantinib are:

as a single agent: decreased appetite, diarrhea, fatigue, PPE, nausea, vomiting, hypertension, weight decreased, constipation, dysphonia.

in combination with nivolumab: hepatotoxicity, diarrhea, fatigue, stomatitis, rash, hypertension, hypothyroidism, musculoskeletal pain, abdominal pain, cough, decreased appetite, nausea, dysgeusia, and upper respiratory tract infection. 

  • Severe and fatal hemorrhages occurred with cabozantinib 60 mg. The incidence of Grade 3-5 hemorrhagic events occurred in patients treated with cabozantinib. Discontinue treatment for Grade 3/4 hemorrhage. Do not administer it to patients who have a known history of hemorrhage, including hematemesis, hemoptysis, or melena.
  • Gastrointestinal (GI) perforations and Fistulas, including fatal cases, occurred in patients treated with cabozantinib. Assess patients for signs and symptoms of fistulas and perforations, including sepsis and abscess. Discontinue therapy in patients who experience a fistula which cannot be precisely managed or a GI perforation. 
  • Cabozantinib increased the risk of thrombotic events. Fatal thrombotic events have been seen in patients treated with Cabozantinib 20 mg, or 40 mg, or 60 mg. Discontinue therapy in patients who develop a serious arterial or acute myocardial infarction or or venous thromboembolic events that require medical intervention. 
  • Treatment with Cabozantinib can be responsible for causing hypertension, including hypertensive crisis. Do not initiate treatment in patients with uncontrolled hypertension. Assess blood pressure regularly throughout the treatment.
  • Diarrhea occurred in patients treated with Cabozantinib. Withhold treatment until improvement to Grade-1 and resume treatment at a reduced dose for intolerable Grade-2 diarrhea, Grade-3 diarrhea that cannot be managed with standard anti diarrhea treatments, or Grade-4 diarrhea. 
  • Proteinuria have been seen in patients receiving Cabozantinib. Monitor urine protein on a regular basis throughout cometriq (Cabozantinib) treatment. Discontinue this medicine in patients who develop nephrotic syndrome. 
  • Cabozantinib may be hazardous to the fetus if administered to a pregnant woman. Females of reproductive age should use effective contraception during treatment with Cabozantinib and for four months after the final dose.

Is Cabozantinib available in the form of capsules? 

Yes. Cabozantinib (Brand-Name: Cometriq) is available in the form of 20 mg/80 mg capsules for progressive, metastatic medullary thyroid cancer (MTC).

What class of drug is Cabozantinib?

Cabozantinib (Cometriq) is in a class of drugs known as TKIs. It works by inhibiting the action of an abnormal protein that indicates cancer cells to multiply. 

How to store the medicine Cabozantinib?

Store Cabozantinib at temperature 20°C to 25°C (68°F to 77°F); excursions are permitted from 15°C to 30°C (59°F to 86°F).

What should one do if someone takes an overdose of Cabozantinib?

There is no known specific treatment for an overdose with Cabozantinib. If a patient takes an overdose, the patient should be monitored, and standard supportive treatment applied as required. 

How much does Cabozantinib cost?

The cabozantinib cost in India is less and reasonable. In order to procure this medicinal product authentically, we request you to Call/WhatsApp Us: (+91) 8130290915, Or dial our TOLL-FREE: 1800-889-1064, Or Write Us: query@indiangenericmedicines.com.

Is Cabozantinib chemotherapy?

Cabozantinib can also be known by their brand names, Cometriq or Cabometyx. This medication is a kind of chemotherapy. 

Where can I get Cabozantinib at the best price from India?

To get the best cabozantinib price from India, always buy or procure this RCC/HCC medicine from Indian Generic Medicines, which is authentically certified by the higher authorities named WHO-GDP & ISO 9001 : 2008. 

Is the drug Cabozantinib available in India?

The drug Cabozantinib is a (prescription drug, doctor-prescribed medication, or health care professional-prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription.

Cabozantinib can be made available through the network of authorized distributors in India. (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Pune, etc.)

Can You Send the Medicine Cabozantinib to Foreign Destinations?

Buy cabozantinib from India online at the best/lowest through a leading supplier. Indian Generic Medicines can assist in the delivery of this medicine; the doctor prescribed medication to the Australia, USA, UK, Canada, China, Thailand, South Africa, Saudi Arabia, Philippines, Zambia, Pakistan, Qatar, Kuwait, Sweden, Hong kong, UAE, Kazakhstan, Turkey, Singapore, Malaysia, Sri Lanka, Uzbekistan, Afghanistan, Nepal, Japan, and many more countries.

Contact Patient Support

If you have any questions or need any help, contact our Patient Support Team. We will get in touch with you within 24 hours from Monday to Friday between 9:00 and 10:00 CET.

Email

Query@Indiangenericmedicines.Com

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Disclaimer

CMV retinitis is kind of an eye infection caused by a virus. CMV mainly attacks the retina of the eye and can be responsible for causing loss of vision, and eventually may lead to the blindness. Patients with acquired immunodeficiency syndrome are more likely to develop CMV retinitis. CMV retinitis is kind of an eye infection caused by a virus. CMV mainly attacks the retina of the eye and can be responsible for causing loss of vision, and eventually may lead to the blindness. Patients with acquired immunodeficiency syndrome are more likely to develop CMV retinitis.

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