Facts of Tagrisso ®
- Medicine Name: Tagrisso ®
- Generic Name: Osimertinib
- Company Name: Astra Zeneca
- Available as (Form & Strength): 80mg Tablets
Tagrisso is a kinase inhibitor indicated for the treatment of patients with metastatic epidermal growth factor receptor (EGFR) T790M mutation positive non-small cell lung cancer (NSCLC), as detected by an FDA approved test, who have progressed on or after EGFR TKI therapy.
Confirm the presence of T790M mutation in tumor specimens prior to initiation of treatment with TAGRISSO.
80 mg orally once daily, with or without food.
Mode of Action
Osimertinib is kinase inhibitor of the epidermal growth factor receptor (EGFR), which binds irreversibly to certain mutant forms of EGFR (T790M, L858R, and exon 19 deletion) at approximately 9-fold lower concentrations than wild-type. In cultured cells and animal tumor implantation models, osimertinib exhibited anti-tumor activity against NSCLC lines harboring EGFR-mutations (T790M/L858R, L858R, T790M/exon 19 deletion, and exon 19 deletion) and, to a lesser extent, wild-type EGFR amplifications. Two pharmacologically-active metabolites (AZ7550 and AZ5104 circulating at approximately 10% of the parent) with similar inhibitory profiles to Osimertinib have been identified in the plasma after oral administration of Osimertinib.
- dizziness, lightheadedness, or fainting
- eye or vision changes
- fast, pounding, or uneven heartbeat
- pain in the chest, groin, or legs, especially the calves
- pain, redness, or swelling in the arm or leg
- slurred speech
- sudden loss of coordination
- sudden, severe headache
- sudden, severe weakness or numbness in the arm or leg
- troubled breathing
Indian Generic Medicines assist you in delivering Tagrisso ® (Osimertinib) across the world as per the customer’s prescribed medication and applicable regulatory approval. Tagrisso ® (Osimertinib) is manufactured by Astra Zeneca.
Indian Generic Medicines is able to get any valid prescription dispensed in shortest possible time. All prescriptions are dispensed and checked by registered pharmacists.
Is Tagrisso ® (Osimertinib) available in India?
Tagrisso ® (Osimertinib) is a (prescription drug, doctor prescribed medication or health care professional prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription.
- Tagrisso ® can be made available through the network of authorised distributors in India. (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc.)
- Please click for Tagrisso ® Price information.
Indian Generic Medicines can assist in the deliver of Tagrisso ® (Osimertinib), doctor prescribed medicine to USA, UK, Canada, Australia, China, Saudi Arabia, Thailand, South Africa, Zambia, Pakistan, Qatar, Kuwait, Sweden, Hong kong, UAE, Philippines, Kazakhstan, Turkey, Hong Kong, Singapore, Malaysia, Sri Lanka, Uzbekistan Afghanistan, Nepal, Japan, and many more countries.
We validate authenticity of suppliers. Our approved suppliers assure supply of genuine medicine against valid documents.
The order will be confirmed only after the receipt of
- Valid prescription of Doctor and
- Import permit if applicable