What is the generic name of Lynparza?
Generic name of Lynparza is Olaparib.
Who is the manufacturer of Lynparza?
Lynparza is manufactured and marketed by Astra Zeneca
Is Lynparza approved by USA FDA?
Yes, Lynparza is approved by FDA. The product was approved in 2014.
What are the storage conditions of Lynparza?
Store un reconstituted vials at 25º C (77º F); excursions permitted to 15º-30º C (59º-86º F).
How Lynparza is supplied?
Lynparza is available in 300mg , 120 tablets packing.
How does Lynparza work?
Lynparza is an inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, including PARP1, PARP2, and PARP3. PARP enzymes are involved in normal cellular functions, such as DNA transcription and DNA repair. Olaparib has been shown to inhibit growth of select tumor cell lines in vitro and decrease tumor growth in mouse xenograft models of human cancer, both as monotherapy or following platinumbased chemotherapy. Increased cytotoxicity and anti-tumor activity following treatment with olaparib were noted in cell lines and mouse tumor models with deficiencies in BRCA and non-BRCA proteins involved in the homologous recombination repair (HRR) of DNA damage and correlated with platinum response.
What is Lynparza used for?
Maintenance Treatment of Recurrent Ovarian Cancer
Lynparza is indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer, who are in a complete or partial response to platinum-based chemotherapy.
Advanced gBRCA-mutated Ovarian Cancer After 3 or More Lines of Chemotherapy
Lynparza is indicated for the treatment of adult patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm) advanced ovarian cancer who have been treated with three or more prior lines of chemotherapy. Select patients for therapy based on an FDA-approved companion diagnostic for Lynparza.
How many brands of Lynparza are available in India?
Lynparza is an innovator medicine. There are no other generics/biosimilars available in India.
Is there any generic or bio similar available for Lynparza.
Biosimilars/ Generics of Lynparza is not available in India.
What is the price of Lynparza in India?
You can call or WhatsApp (+91) 9650877511 or send mail to firstname.lastname@example.org to know the price.
Is it safe to buy Lynparza in India from local distributor?
It is always better to check the credential of the person / distributor before confirming.
As per the legal guidelines, only patients can import the product after getting proper Documentation.