What is the generic name of Hertraz?
Generic name of Hertraz is Traztuzumab.
Who is the manufacturer of Hertraz?
Hertraz is manufactured by Biocon Ltd. and marketed by Mylan Pharma Pvt. Ltd.
Is Hertraz approved by USA FDA?
Yes, Hertraz is approved by FDA. The product was approved in 1998.
What is the dosage form of Hertraz?
Hertraz is available as 150mg and 440mg , single vial for Injection
What are the storage conditions of Hertraz?
The product should be stored at 2° to 8°C. Hertraz vials should be protected from light. Do not freeze or shake.
How Hertraz is supplied?
Hertraz is supplied as single vial for injection in strength of 150mg and 440mg.
How does Hertraz 150mg and 440mg work?
The HER2 (or c-erbB2) proto-oncogene encodes a transmembrane receptor protein of 185 kDa, which is structurally related to the epidermal growth factor receptor. Herceptin has been shown, in both in vitro assays and in animals, to inhibit the proliferation of human tumor cells that overexpress HER2. Hertraz is a mediator of antibody-dependent cellular cytotoxicity (ADCC). In vitro, Hertraz-mediated ADCC has been shown to be preferentially exerted on HER2 overexpressing cancer cells compared with cancer cells that do not overexpress HER2.
What is Hertraz 150mg and 440mg used for?
Adjuvant Breast Cancer
Hertraz is indicated for adjuvant treatment of HER2 overexpressing node positive or node negative (ER/PR negative or with one high risk feature breast cancer
• as part of a treatment regimen consisting of doxorubicin, cyclophosphamide, and either paclitaxel or docetaxel
• as part of a treatment regimen with docetaxel and carboplatin
• as a single agent following multi-modality anthracycline based therapy. Select patients for therapy based on an FDA-approved companion diagnostic for Herceptin.
Metastatic Breast Cancer
Hertraz is indicated:
• In combination with paclitaxel for first-line treatment of HER2-overexpressing metastatic breast cancer • As a single agent for treatment of HER2-overexpressing breast cancer in patients who have received one or more chemotherapy regimens for metastatic disease. Select patients for therapy based on an FDA-approved companion diagnostic for Hertraz.
Metastatic Gastric Cancer
Hertraz is indicated, in combination with cisplatin and capecitabine or 5-fluorouracil, for the treatment of patients with HER2-overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma who have not received prior treatment for metastatic disease.
Is there any generic or bio similar available for Hertraz 150mg and 440mg.
Biosimilar of Hertraz are available in India.
What is the price of Hertraz 150mg and 440mg in India?
You can call or WhatsApp (+91) 9650877511 or send mail to firstname.lastname@example.org to know the price.
Other information about Hertraz 150mg and 440mg.
MUMBAI and PITTSBURGH, Feb. 3, 2014 /PRNewswire/ — Mylan Inc. (Nasdaq: MYL), one of the world’s leading generic and specialty pharmaceutical companies, today announced that its subsidiary, Mylan Pharmaceuticals Private Limited, has launched the world’s first trastuzumab biosimilar in India. The product, which will be marketed by Mylan under the brand name HertrazTM, is a biosimilar to Roche’s Herceptin®. Hertraz is indicated for the treatment of HER2-positive metastatic breast cancer and is available in two strengths, 440 mg and 150 mg.
Is it safe to buy Hertraz 150mg and 440mg in India from local distributor?
It is always better to check the credential of the person / distributor before confirming.
As per the legal guidelines, only patients can import the product after getting proper Documentation.