Facts of Alecensa
- Medicine Name: Alecensa®
- Generic Name: Alectinib
- Company Name: Roche
- Available as (Form & Strength):150mg ,224 capsules
Alecensa is a kinase inhibitor indicated for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive, metastatic non-small cell lung cancer (NSCLC) who have progressed on or are intolerant to crizotinib. This indication is approved under accelerated approval based on tumor response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials.
600 mg orally twice daily. Administer ALECENSA with food.
Mechanism of Action
Alectinib is a tyrosine kinase inhibitor that targets ALK and RET. In nonclinical studies, alectinib inhibited ALK phosphorylation and ALK-mediated activation of the downstream signaling proteins STAT3 and AKT, and decreased tumor cell viability in multiple cell lines harboring ALK fusions, amplifications, or activating mutations.
- Bloody urine
- chest pain or discomfort
- decreased frequency or amount of urine
- difficulty with moving
- increased blood pressure
- increased thirst
- joint pain or swelling
- loss of appetite
- lower back or side pain
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Is Alecensa available in India?
Alecensa is a (prescription drug, doctor prescribed medication or health care professional prescribed medicine) pharmaceutical drug that can be legally dispensed against a medical prescription.
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